K. Stephen Brown

Principal Investigator

University of Waterloo


K. Stephen Brown is a biostatistician, Professor and a former Chair of the Department of Statistics and Actuarial Science, and Director of Biostatistics at the Propel Centre for Population Health Impact at the University of Waterloo. He also holds a cross-appointment in the School of Public Health and Health Systems. His interests include design and analysis of cluster-randomized prevention trials, correlated discrete response data, generalized linear models, statistical consulting, and statistics education. Dr. Brown has studied the design and analysis of smoking prevention program trials since the first randomized trial of the Waterloo Smoking Prevention Project (WSPPI) began in 1979. He was involved with a seven-year longitudinal, randomized trial (WSPP3) involving approximately 6000 students in 100 elementary schools in South Western Ontario that ran from 1990 – 1996 and was principal investigator on a randomized trial (WSPP4) examining whether a technical assistance package offered to secondary schools will increase their use of effective tobacco use control interventions and, subsequently, reduce teen smoking rates. He was an author of the Technical Reports of the 1994 and 2002 Health Canada Youth Smoking Surveys, and has been a co-investigator on the biennial national Youth Smoking Surveys from the 2004/2005 survey to the present (2012/2013).

He was a co-principal investigator on a the Impact study, a CIHR funded national study that investigated the role of individual, school program and policy, and community characteristics on adolescent tobacco use, and is currently a co-investigator on the COMPASS study, a longitudinal study of high-school aged students that will investigate the role of individual, school and community factors on behavioural factors including smoking, physical activity, healthy eating and other drug use. In addition, he is involved with several studies on the use of social media to increase the reach and effectiveness of 1-800 lines for smoking cessation.

Competing Interest Statement

K. Stephen Brown, OTRU Principal Investigator, is a Professor in the Department of Statistics and Actuarial Science and Director of Biostatistics for the Propel Centre for Population Health Impact at the University of Waterloo. Dr. Brown has had no relationship with the tobacco industry. He is a member of a team that has a contract with Public Works, Government Services, Canada, for the Youth Smoking Survey. He is an investigator on grants from the Canadian Cancer Society Research Initiative, the Canadian Institutes of Health Research (CIHR), the National Institutes of Health (US), the Ontario Ministry of Health and Long Term Care, and the International Development Research Centre. He is part of a group that receives funds from the Bill and Melinda Gates Foundation. In the past few years, he has had a contract with a pharmaceutical company for statistical consulting services for a non-tobacco product; has accepted honoraria from the Michael Smith Foundation for a grant review; has received funds to attend and speak at the Annual Invitational Symposium for Research in Tobacco Control; and his expenses to participate in CIHR grant review panel were covered by CIHR.

Selected Publications

Lovato CY, Watts AW, Brown KS, Lee DG, Sabiston CM, Nykiforuk C, et al. School and community predictors of smoking: a longitudinal study of Canadian high schools. In press: American Journal of Public Health.

Diemert L, Bondy S, Brown KS, Manske S. Young adult smoking cessation: what predicts success? In press: American Journal of Public Health.

Mecredy GC, Bondy SJ, Brown KS, Cohen JE. Cigarette type ‘switchers’: A descriptive analysis. Canadian Journal of Public Health 2011 Nov-Dec; 102(6): 477-8 (letter).

Smith PM, Corso L, Brown KS, Cameron R, Winfield D. Nurse case-managed tobacco cessation interventions for general hospital patients: results of a randomized clinical trial. Canadian Journal of Nursing Research 2011 Mar; 43(1): 98-117.

Sendzik T, McDonald PW, Brown KS, Hammond D, Ferrence R. Planned quit attempts among Ontario smokers: impact on abstinence. Addiction 2011 Nov; 106(11): 2005-13.

Lovato C, Zeisser C, Campbell HS, Pullman A, Halpin P, Thompson ME, Eyles J, Adlaf E, Brown KS. Adolescent smoking: effect of school and community characteristics. American Journal of Preventive Medicine 2010 Dec; 39(6):507-514.